Chloroquine Phosphate 5MLml vials are designed for intramuscular or subcutaneous injection, primarily for treating severe malaria, with a typical strength of base/mL (or sometimes phosphate equivalent per mL). These, such as Lariago, are prescription-only, liquid-form, multi-dose glass vials often containing benzyl alcohol as a preservative.
Key Specifications & Details:
Active Ingredient: Chloroquine Phosphate BP/USP.
Concentration: base/mL ( per vial total).
Form: Liquid solution for injection (intramuscular/subcutaneous).
Packaging:
glass vial, often in multi-dose, with preservatives.
Common Brand/Manufacturer: Lariago (Ipca Laboratories), Syncom
Formulations.
Indications: Treatment of malaria, amoebiasis, and sometimes, acute arthritis.
Storage: Typically stored in a cool, dry place, protected from direct sunlight.
Shelf Life: Approximately months. Composition (Typical):Chloroquine Phosphate:
(equivalent to Chloroquine base).Preservative: Benzyl Alcohol BP Vehicle: Water
for Injection.
Physical Form
Liquid
Recommended For
HUMAN BEING
Dosage
As Per Suggestion
Quantity
10000 Unit
About CHLOROQUINE INJ 5ML
Chloroquine Phosphate Injection (40mg/mL) in 5ml ampoules is a sterile, parenteral antimalarial agent used for treating acute or severe malaria when oral therapy is not possible. It acts by inhibiting heme polymerase, and is administered via intramuscular or slow intravenous infusion. It is also used to treat hepatic amoebiasis.
Key Information regarding 40mg/mL, 5ml Ampoules:
Indications: Treatment of acute malaria caused by P. falciparum, P. malariae, P. vivax, and P. ovale.
Administration: Must be administered slowly (IV) or by deep intramuscular injection. Rapid IV injection can cause severe hypotension or cardiac arrest.
Dosage Information: Often provided as a 5ml ampoule (containing 200mg base) which is typically diluted for use.
Side Effects: Common adverse effects include pruritus (itching), headache, visual disturbances, and gastrointestinal issues.
Contraindications/Precautions: Use with caution in patients with hepatic impairment, renal impairment, or porphyria. It is important to monitor cardiac function (ECG) during parenteral administration.
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Description and Composition
Active Ingredient: Metoprolol tartrate, USP.
Form: A sterile, clear, colorless, preservativefree solution for intravenous (IV) administration.
Strength: 1 mg of metoprolol tartrate per 1 mL of solution.
Inactive Ingredients: Sodium chloride (for isotonicity) and water for injection.
pH: 5.0 to 8.0.
Indications and Usage
Metoprolol IV is used in a hospital or emergency setting for:
Acute Myocardial Infarction (Heart Attack): To reduce cardiovascular mortality in hemodynamically stable patients.
Arrhythmias: To treat rapid heart rate, such as supraventricular tachycardia.
Perioperative Tachycardia: To control heart rate during anesthesia.
Mechanism of Action
Metoprolol is a selective 1adrenoreceptor blocker. It works by:
Slowing Heart Rate: Reduces resting heart rate (negative chronotropic effect).
Lowering Blood Pressure: Decreases systolic blood pressure.
Reducing Contractility: Decreases how hard the heart muscle contracts (negative inotropic effect), thus lowering oxygen demand.
Contraindications
This medication should not be used in patients with:
Heart rate < 45 beats/min.
Second or thirddegree heart block.
Significant firstdegree heart block.
Systolic blood pressure < 100 mmHg.
Moderatetosevere cardiac failure.
Side Effects
Common side effects include:
Cardiovascular: Bradycardia (slow heart rate), hypotension (low blood pressure), dizziness.
Other: Fatigue, cold extremities, shortness of breath, or diarrhea